You are watching: 4-bromo-1-butene
4-Bromo-1-butene was offered in the synthesis of 4-(3-butenyloxy)benzoic acid. That was likewise used in the total synthesis that largazole. The was supplied in double alkylation of lactams, followed by Grubbs ring-closing metathesis, to productivity gymnodimine (biotoxin).It was supplied in ready of dienehydrazides.
Full details that the concise and also convergent synthesis (eight steps, 19% in its entirety yield), its expansion to the ready of a series of key analogues, and the molecular target and also pharmacophore of largazole space described. Main to the synthetic of largazole...
Thiol-ene radical coupling is significantly used for the biofunctionalization the biomaterials and the formation of 3D hydrogels permitting cell encapsulation. Indeed, thiol-ene chemistry presents interesting features the are particularly attractive because that platforms requiring particular reactions the peptides or proteins, in...
Stereoselective epoxidation the 4-bromo-1-butene and also 3-butene-1-ol with 3 alkene-utilizing bacteria.
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